Neuronal Polarization Packs a One-Two Punch
- PMID: 30521770
- DOI: 10.1016/j.neuron.2018.11.022
Neuronal Polarization Packs a One-Two Punch
Abstract
In this issue of Neuron, Ambrozkiewicz et al. (2018) define a new molecular circuit controlling neuronal polarization and migration through the transcription factor SOX9 to coordinate the production of regulators of both protein synthesis and degradation.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
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Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140.Neuron. 2018 Dec 5;100(5):1097-1115.e15. doi: 10.1016/j.neuron.2018.10.008. Epub 2018 Nov 1. Neuron. 2018. PMID: 30392800
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