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Comment
. 2018 Dec 5;100(5):1014-1016.
doi: 10.1016/j.neuron.2018.11.036.

CHD2: One Gene, Many Roles

Vanesa Nieto-Estevez  1 , Jenny Hsieh  2
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CHD2: One Gene, Many Roles

Vanesa Nieto-Estevez et al. Neuron. .
Free article

Abstract

Mutations in the chromodomain helicase DNA-binding 2 (CHD2) gene have been found in patients with a range of neurodevelopmental disorders. In this issue of Neuron, Kim et al. (2018) showed that Chd2 haploinsufficiency compromises cortical development, synaptic function, and memory in mice.

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