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Review
. 2019 Jun;44(6):1271-1278.
doi: 10.1007/s11064-018-2690-9. Epub 2018 Dec 6.

Diabetes and Alzheimer's Disease: A Link not as Simple as it Seems

Isabel H Salas  1   2 , Bart De Strooper  3   4   5
Affiliations
Review

Diabetes and Alzheimer's Disease: A Link not as Simple as it Seems

Isabel H Salas et al. Neurochem Res. 2019 Jun.

Abstract

Type 2 diabetes mellitus is associated with an increased risk to develop Alzheimer disease, however, the underlying mechanisms for this association are still unclear. In this review we will provide a critical overview of the major findings coming from clinical studies and animal models.

Keywords: Alzheimer’s disease; Amyloid; Cognition; Dementia; Diabetes; Glycemia; Insulin; Metabolic stress.

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References

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