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Review
. 2018 Dec 8;12(1):363.
doi: 10.1186/s13256-018-1920-8.

Mitral valve myxoma presenting with transient ischemic attack: a case report and review of the literature

Kendra J Grubb  1 , Vasa Jevremovic  2 , Edgar G Chedrawy  3   4
Affiliations
Review

Mitral valve myxoma presenting with transient ischemic attack: a case report and review of the literature

Kendra J Grubb et al. J Med Case Rep. .

Abstract

Background: Myxomas account for approximately half of all primary cardiac neoplasms. Most occur in the left atrium and only rarely are attached to the mitral valve, with just over 30 such cases reported in the literature. These neoplasms can manifest with a combination of obstruction of blood flow, systemic embolization, and constitutional symptoms.

Case description: We present a case of a 32-year-old African American man presenting at an emergency department with symptoms of a transient ischemic attack. Transesophageal echocardiography identified a mass originating from the posterior leaflet of the mitral valve. The mass was surgically resected and histologically classified as a myxoma. He remained asymptomatic during the course of 5-year surveillance.

Conclusions: Few similar cases have been described in the literature. Here we present a review of the diagnosis and surgical management of this rare presentation for mitral valve myxoma.

Keywords: Cardiac myxoma; Cardiac neoplasm; Case report; Mitral valve myxoma.

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Conflict of interest statement

Ethics approval and consent to participate

Not applicable.

Consent for publication

Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.

Competing interests

The authors declare that they have no competing interests.

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Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
Myxoma case timeline. CT computed tomography, EKG electrocardiogram, MRI magnetic resonance imaging, TEE transesophageal echocardiogram, tPA tissue plasminogen activator, TTE transthoracic echocardiography
Fig. 2
Fig. 2
Transesophageal echocardiogram depicting mitral valve mass
Fig. 3
Fig. 3
Intraoperative image: mitral valve myxoma. Arrow points to 2 × 3 cm pedunculated, soft, and polypoid mass arising from posterior leaflet of mitral valve
See this image and copyright information in PMC

References

    1. Pucci A, Gagliardotto P, Zanini C, et al. Histopathologic and clinical characterization of cardiac myxoma: Review of 53 cases from a single institution. Am Heart J. 2000;140(1):134–138. doi: 10.1067/mhj.2000.107176. - DOI - PubMed
    1. Reynen K. Frequency of primary tumors of the heart. Am J Cardiol. 1996;77:107. doi: 10.1016/S0002-9149(97)89149-7. - DOI - PubMed
    1. Roberts WC. Primary and secondary neoplasms of the heart. Am J Cardiol. 1997;80:671–682. doi: 10.1016/S0002-9149(97)00587-0. - DOI - PubMed
    1. Butany J, Nair V, Naseemuddin A, et al. Cardiac tumors: diagnosis and management. Lancet Oncol. 2005;6:219–228. doi: 10.1016/S1470-2045(05)70093-0. - DOI - PubMed
    1. Reynen K. Cardiac myxoma. N Engl J Med. 1996;333:1610–1617. doi: 10.1056/NEJM199512143332407. - DOI - PubMed