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. 2018 Dec;39(12):1480-1483.
doi: 10.1017/ice.2018.244.

Variability of surgical prophylaxis in penicillin-allergic children

David F Butler  1 , Brian R Lee  1 , Sarah Suppes  2 , Tracy Sandritter  2 , Jason G Newland  3 , Lory Harte  2 , Jennifer L Goldman  1
Affiliations

Variability of surgical prophylaxis in penicillin-allergic children

David F Butler et al. Infect Control Hosp Epidemiol. 2018 Dec.

Abstract

We retrospectively evaluated the effect of penicillin adverse drug reaction (ADR) labeling on surgical antibiotic prophylaxis. Cefazolin was administered in 86% of penicillin ADR-negative (-) and 28% penicillin ADR-positive (+) cases. Broad-spectrum antibiotic use was more common in ADR(+) cases and was more commonly associated with perioperative adverse drug events.

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