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Comment
. 2018 Dec 6;23(6):782-783.
doi: 10.1016/j.stem.2018.10.025.

Considerations for Assessing the Extent of Hippocampal Neurogenesis in the Adult and Aging Human Brain

Affiliations
Comment

Considerations for Assessing the Extent of Hippocampal Neurogenesis in the Adult and Aging Human Brain

Alexandria N Tartt et al. Cell Stem Cell. .
No abstract available

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Conflict of interest statement

DECLARATION OF INTERESTS

A.J.D. received gifts from Olympus and Visio-pharm, R.H. received compensation as a consultant for Roche and Lundbeck, and J.J.M. received royalties for commercial use of the C-SSRS from the Research Foundation for Mental Hygiene.

Comment on

  • Human Hippocampal Neurogenesis Persists throughout Aging.
    Boldrini M, Fulmore CA, Tartt AN, Simeon LR, Pavlova I, Poposka V, Rosoklija GB, Stankov A, Arango V, Dwork AJ, Hen R, Mann JJ. Boldrini M, et al. Cell Stem Cell. 2018 Apr 5;22(4):589-599.e5. doi: 10.1016/j.stem.2018.03.015. Cell Stem Cell. 2018. PMID: 29625071 Free PMC article.
  • Does Adult Neurogenesis Persist in the Human Hippocampus?
    Paredes MF, Sorrells SF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S, Chang J, Auguste KI, Chang EF, Gutierrez Martin AJ, Kriegstein AR, Mathern GW, Oldham MC, Huang EJ, Garcia-Verdugo JM, Yang Z, Alvarez-Buylla A. Paredes MF, et al. Cell Stem Cell. 2018 Dec 6;23(6):780-781. doi: 10.1016/j.stem.2018.11.006. Cell Stem Cell. 2018. PMID: 30526879 Free PMC article. No abstract available.

References

    1. Boldrini M, Hen R, Underwood MD, Rosoklija GB, Dwork AJ, Mann JJ, and Arango V (2012). Hippocampal angiogenesis and progenitor cell proliferation are increased with antidepressant use in major depression. Biol. Psychiatry 72, 562–571. - PMC - PubMed
    1. Boldrini M, Fulmore CA, Tartt AN, Simeon LR, Pavlova I, Poposka V, Rosoklija GB, Stankov A, Arango V, Dwork AJ, et al. (2018). Human hippocampal neurogenesis persists throughout aging. Cell Stem Cell 22, 589–599.e5. - PMC - PubMed
    1. Braun N, Papadopoulos T, and Müller-Herme-link HK (1988). Cell cycle dependent distribution of the proliferation-associated Ki-67 antigen in human embryonic lung cells. Virchows Arch. B Cell Pathol. Incl. Mol. Pathol 56, 25–33. - PubMed
    1. Encinas JM, Michurina TV, Peunova N, Park JH, Tordo J, Peterson DA, Fishell G, Koulakov A, and Enikolopov G (2011). Division-coupled astrocytic differentiation and age-related depletion of neural stem cells in the adult hippo-campus. Cell Stem Cell 8, 566–579. - PMC - PubMed
    1. Eriksson PS, Perfilieva E, Björk-Eriksson T, Alborn AM, Nordborg C, Peterson DA, and Gage FH (1998). Neurogenesis in the adult human hippocampus. Nat. Med 4, 1313–1317. - PubMed

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