Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Jul 12;7(1):e00835-18.
doi: 10.1128/MRA.00835-18. eCollection 2018 Jul.

Sequence Variation in Multidrug-Resistant Plasmid pLUH01, Isolated from Human Nasopharyngeal Swabs

Kate V Atkinson  1 , Lisa A Bishop  1   2 , Glenn Rhodes  3 , Nicolas Salez  4 , Neil R McEwan  5 , Matthew J Hegarty  5 , Julie Robey  6 , Nicola Harding  6 , Simon Wetherell  6 , Robert M Lauder  1 , Roger W Pickup  1 , Mark Wilkinson  2 , Derek Gatherer  1
Affiliations

Sequence Variation in Multidrug-Resistant Plasmid pLUH01, Isolated from Human Nasopharyngeal Swabs

Kate V Atkinson et al. Microbiol Resour Announc. .

Abstract

Three variants of the multidrug-resistant plasmid pLUH01 were assembled by deep sequencing from nasopharyngeal swabs. All have a 21-bp deletion in the RS14515 hypothetical gene. Variants 1 through 3 have 2, 6, and 3 nucleotide substitutions, respectively, compared to the pLUH01 reference genome. We named the new plasmid variants pLUH01/Lancaster/2015/1 to pLUH01/Lancaster/2015/3.

PubMed Disclaimer

References

    1. Lindqvist M, Isaksson B, Grub C, Jonassen TØ, Hallgren A. 2012. Detection and characterisation of SCCmec remnants in multiresistant methicillin-susceptible Staphylococcus aureus causing a clonal outbreak in a Swedish county. Eur J Clin Microbiol Infect Dis 31:141–147. doi:10.1007/s10096-011-1286-y. - DOI - PubMed
    1. Im SH, Yoon SJ, Kim WK, Shin CK, Lee DW, Moon KH. 1996. Characterization of cryptic plasmid of multidrug-resistant Staphylococcus aureus SA2. J Microbiol Biotechnol 6:145–146.
    1. Bjorland J, Steinum T, Sunde M, Waage S, Heir E. 2003. Novel plasmid-borne gene qacJ mediates resistance to quaternary ammonium compounds in equine Staphylococcus aureus, Staphylococcus simulans, and Staphylococcus intermedius. Antimicrob Agents Chemother 47:3046–3052. doi:10.1128/AAC.47.10.3046-3052.2003. - DOI - PMC - PubMed
    1. Atkinson KV, Bishop LA, Rhodes G, Salez N, McEwan NR, Hegarty MJ, Robey J, Harding N, Wetherell S, Lauder RM, Pickup RW, Wilkinson M, Gatherer D. 2017. Nasopharyngeal metagenomic deep sequencing data, Lancaster, UK, 2014–2015. Sci Data 4:170161. doi:10.1038/sdata.2017.161. - DOI - PMC - PubMed
    1. Atkinson KV, Bishop LA, Rhodes G, Salez N, McEwan NR, Hegarty MJ, Robey J, Harding N, Wetherell S, Lauder RM, Pickup RW, Wilkinson M, Gatherer D. 2017. Influenza C in Lancaster, UK, in the winter of 2014–2015. Sci Rep 7:46578. doi:10.1038/srep46578. - DOI - PMC - PubMed

LinkOut - more resources