Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019:1916:99-103.
doi: 10.1007/978-1-4939-8994-2_9.

The Open Field Test for Measuring Locomotor Activity and Anxiety-Like Behavior

Ann-Katrin Kraeuter  1   2 , Paul C Guest  3 , Zoltán Sarnyai  4   5
Affiliations

The Open Field Test for Measuring Locomotor Activity and Anxiety-Like Behavior

Ann-Katrin Kraeuter et al. Methods Mol Biol. 2019.

Abstract

The open field test is used in studies of the neurobiological basis of anxiety and screening for novel drug targets and anxiolytic compounds. This test uses a camera to measure movement of the test animal in the peripheral and central zones of a 42 × 42 × 42 cm polyvinyl chloride box. This chapter describes a protocol for carrying out the open-field test for assessment of locomotion and anxiety-like behavior in mice.

Keywords: Anxiety; Behavior; Locomotion; Open-filed; Psychiatric disorder.

PubMed Disclaimer

Substances