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Review
. 2018 Dec 12;10(471):eaao5333.
doi: 10.1126/scitranslmed.aao5333.

Big data and black-box medical algorithms

Affiliations
Review

Big data and black-box medical algorithms

W Nicholson Price. Sci Transl Med. .

Abstract

New machine-learning techniques entering medicine present challenges in validation, regulation, and integration into practice.

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Conflict of interest statement

Competing interests: The author declares no competing interests.

Figures

Fig. 1.
Fig. 1.
Validation of black-box algorithms. Computational validation of black-box algorithms involves three related steps: 1) ensuring basic quality of training data and development procedures; 2) testing algorithm performance against independent test data; and 3) evaluating performance in ongoing use. Data from real-world use can be used to improve further iterations of the algorithm.

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