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Review
. 2018 Dec;16(6):4315-4321.
doi: 10.3892/etm.2018.6780. Epub 2018 Sep 19.

Bronchopulmonary dysplasia: Pathogenesis and treatment

Asfia Banu Pasha  1 , Xiao-Qing Chen  1 , Guo-Ping Zhou  1
Affiliations
Review

Bronchopulmonary dysplasia: Pathogenesis and treatment

Asfia Banu Pasha et al. Exp Ther Med. 2018 Dec.

Abstract

Bronchopulmonary dysplasia (BPD) is a form of chronic lung disease of infancy, which mostly affects premature infants with significant morbidity and mortality. Premature infants who require to be treated for conditions including respiratory distress syndrome have a higher risk of developing BPD. In spite of the improvement in clinical methods, the incidence of BPD has not reduced. In the present review, the pathogenesis of BPD is described along with the treatments available at present and the role of nursing in the management of BPD. Emerging preventive therapies for BPD are also discussed, including the use of recombinant human superoxide dismutase, which has been proven effective in reducing respiratory injury and its long-term effects.

Keywords: bronchopulmonary dysplasia; hyperoxia; inflammation; preterm.

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