Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Aug 27;4(3):e179-e182.
doi: 10.1016/j.jccase.2011.07.008. eCollection 2011 Dec.

Aortic valve endocarditis and cerebral mycotic aneurysm due to brucellosis

Affiliations

Aortic valve endocarditis and cerebral mycotic aneurysm due to brucellosis

Refik Emre Altekin et al. J Cardiol Cases. .

Abstract

Brucellosis is an infectious disease caused by Gram-negative coccobacilli. Direct contact with the infected tissue or blood, consumption of infected dairy products, and inhalation of infectious aeresol particles can transmit the disease. Brucella endocarditis is rare but the most fatal complication of brucellosis. The most commonly involved valve is aortic valve. Mycotic aneurysms result as an involvement of central nervous system and can lead to serious complications. Herein we present a case with mycotic aneurysmal rupture and aortic insufficency and sinus valsalva fistula caused by brucella endocarditis. There were rare cases with brucella endocarditis and mycotic aneursymal rupture secondary to neurobrucellosis in the literature. Relevant complications are treated with aortic valve surgery and peripheral endovascular intervention.

Keywords: Brucellosis; Endocarditis; Mycotic aneurysm.

PubMed Disclaimer

Figures

Figure 1
Figure 1
(Left panel) Magnetic resonance image of the subacute phase hemorhagic zone at right thalamus. (Right panel) Magnetic resonance angiographic image of aneurysm of right posterior cerebral artery.
Figure 2
Figure 2
(Left panel) Echocardiographic image of bicuspid aortic valve, with a vegetation formation on aortic cusp and a fistula between aorta and right atrium as a result of ruptured right sinus valsalva. (Right panel) Transesophageal echocardiographic image of vegetation on aortic cusp. LA, left atrium; RA, right atrium; RV, right ventricle.
Figure 3
Figure 3
(Left panel) Angiographic image of right posterior cerebral artery aneurysm. (Right panel) Angiographic image of embolized posterior cerebral artery aneurysm.

Similar articles

References

    1. Young E.J. Brucella species. In: Mandell G.L., Douglas J.E., Bennett R., editors. Mandell, Douglas, and Bennett's principles and practice of infectious disease. 4th ed. Churchill Livingstone; Oxford: 2000. pp. 2386–2391.
    1. Inan M.B., Eyileten Z.B., Ozcinar E., Yazicioglu L., Sirlak M., Eryilmaz S., Akar R., Uysalel A., Tasoz R., Eren N.T., Aral A., Kaya B., Ucanok K., Corapcioglu T., Ozyurda U. Native valve Brucella endocarditis. Clin Cardiol. 2010;33:E20–E26. - PMC - PubMed
    1. Gul H.C., Erdem H., Bek S. Overview of neurobrucellosis: a pooled analysis of 187 cases. Int J Infect Dis. 2009;13:e339–e343. - PubMed
    1. Memish Z., Mah M.W., Al Mahmoud S., Al Shaalan M., Khan M.Y. Brucella bacteraemia: clinical and laboratory observations in160 patients. J Infect. 2000;40:59–63. - PubMed
    1. Jacobs P., Abramowicz D., Vereerstraeten P., Le Clerc J.L., Zech F., Thys J.P. Brucella endocarditis: the role of combined medical and surgical treatment. Rev Infect Dis. 1990;12:740–744. - PubMed

LinkOut - more resources