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. 2019 Jun;38(6):608-610.
doi: 10.1097/INF.0000000000002268.

Acceptability of a Novel Levofloxacin Dispersible Tablet Formulation in Young Children Exposed to Multidrug-resistant Tuberculosis

Susan E Purchase  1 , Anthony J Garcia-Prats  1 , Petra De Koker  1 , Heather R Draper  1 , Muhammad Osman  1 , James A Seddon  1   2 , H Simon Schaaf  1 , Anneke C Hesseling  1
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Free article

Acceptability of a Novel Levofloxacin Dispersible Tablet Formulation in Young Children Exposed to Multidrug-resistant Tuberculosis

Susan E Purchase et al. Pediatr Infect Dis J. 2019 Jun.
Free article

Abstract

Levofloxacin is used for the treatment and prevention of multidrug-resistant tuberculosis in children, but current adult formulations are poorly palatable. A questionnaire administered to caregivers of 27 children taking a novel 100 mg dispersible taste-masked levofloxacin tablet found the new formulation to be more palatable (69%) and easier to prepare (81%) than the adult formulation. This formulation may assist children to better adhere to anti-tuberculous therapy.

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