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Comparative Study
. 2019 Apr;157(4):1313-1321.e2.
doi: 10.1016/j.jtcvs.2018.10.139. Epub 2018 Nov 14.

Late outcomes of strategic arch resection in acute type A aortic dissection

Bo Yang  1 , Elizabeth L Norton  2 , Terry Shih  3 , Linda Farhat  3 , Xiaoting Wu  3 , Whitney E Hornsby  4 , Karen M Kim  3 , Himanshu J Patel  3 , G Michael Deeb  3
Affiliations
Comparative Study

Late outcomes of strategic arch resection in acute type A aortic dissection

Bo Yang et al. J Thorac Cardiovasc Surg. 2019 Apr.

Abstract

Objective: To compare perioperative and long-term outcomes in patients undergoing hemiarch and aggressive arch replacement for acute type A aortic dissection (ATAAD).

Methods: From 1996 to 2017, we compared outcomes of hemiarch (n = 322) versus aggressive arch replacements (zones 2 and 3 arch replacement with implantation of 2-4 arch branches, n = 150) in ATAAD. Indications for aggressive arch were arch aneurysm >4 cm or intimal tear in the aortic arch that was not resectable by hemiarch replacement, or dissection of arch branches with malperfusion.

Results: Patients in the aggressive arch group were significantly younger (mean age: 57 vs 61 years old) and had significantly longer hypothermic circulatory arrest, cardiopulmonary bypass, and aortic crossclamp times. There were no significant differences in perioperative outcomes between hemiarch and aggressive arch groups, including 30-day mortality (5.3% vs 7.3%, P = .38) and postoperative stroke rate (7% vs 7%, P = .96). Over 15 years, Kaplan-Meier survival was similar between hemiarch and aggressive arch groups (log-rank P = .55, 10-year survival 70% vs 72%). Given death as a competing factor, incidence rates of reoperation over 15 years (2.1% vs 2.0% per year, P = 1) and 10-year cumulative incidence of reoperation (14% vs 12%, P = .89) for arch and distal aorta pathology were similar between the 2 groups.

Conclusions: Both hemiarch and aggressive arch replacement are appropriate approaches for select patients with ATAAD. Aggressive arch replacement should be considered for an arch aneurysm >4 cm or an intimal tear at the arch unable to be resected by hemiarch replacement, or dissection of the arch branches with malperfusion.

Keywords: acute type A aortic dissection; aortic arch surgery; aortic dissection; long-term outcome; total arch replacement.

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Figures

Figure 1:
Figure 1:
Kaplan-Meier long-term survival of patients with acute type A aortic dissection undergoing hemiarch or aggressive arch replacement.
Figure 2:
Figure 2:
A. The cumulative incidence of only reoperation for aortic arch and distal aorta, including sternotomy for arch pathology, open repair of descending thoracic or thoracoabdominal aortic aneurysm, and TEVAR, adjusting for death as the competing event. B. The cumulative incidence of all reoperation for any aortic pathology, including aortic root, ascending aorta, arch, and distal aorta, adjusting for death as the competing event.
Figure 2:
Figure 2:
A. The cumulative incidence of only reoperation for aortic arch and distal aorta, including sternotomy for arch pathology, open repair of descending thoracic or thoracoabdominal aortic aneurysm, and TEVAR, adjusting for death as the competing event. B. The cumulative incidence of all reoperation for any aortic pathology, including aortic root, ascending aorta, arch, and distal aorta, adjusting for death as the competing event.
See this image and copyright information in PMC

Comment in

References

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