Triskelion channels might bring Star Wars to the global problem of hypertension
- PMID: 30554719
- DOI: 10.1016/j.ceca.2018.12.005
Triskelion channels might bring Star Wars to the global problem of hypertension
Abstract
In a compelling new report Zeng et al. (Science 2018) suggest that neuronal Piezo1 and Piezo2 channels sense blood pressure in major arteries above the heart [1]. The data challenge previous proposed baroreceptor mechanisms and add to prior knowledge of Piezo1 channels as sensors of blood flow and key players generally in cardiovascular biology.
Copyright © 2018 Elsevier Ltd. All rights reserved.
Comment on
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PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex.Science. 2018 Oct 26;362(6413):464-467. doi: 10.1126/science.aau6324. Science. 2018. PMID: 30361375 Free PMC article.
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