Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Jan;21(1):105-107.
doi: 10.5853/jos.2018.01998. Epub 2018 Dec 18.

Recanalization before Thrombectomy in Tenecteplase vs. Alteplase-Treated Drip-and-Ship Patients

Affiliations

Recanalization before Thrombectomy in Tenecteplase vs. Alteplase-Treated Drip-and-Ship Patients

Pierre Seners et al. J Stroke. 2019 Jan.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors have no financial conflicts of interest.

Figures

Figure 1.
Figure 1.
Association between early recanalization (ER) rate and time elapsed between intravenous thrombolysis (IVT) start and ER assessment in the present study and the Extending the time for Thrombolysis in Emergency Neurological Deficits–Intra-Arterial using Tenecteplase (EXTEND-IA TNK) trial. The red and blue bars in the lower left corner represent the duration of tenecteplase or alteplase intravenous administration. Red and blue squares represent ER incidence following tenecteplase and alteplase, espectively. Bars represent the 95% confidence intervals.

References

    1. Campbell BCV, Mitchell PJ, Churilov L, Yassi N, Kleinig TJ, Dowling RJ, et al. Tenecteplase versus alteplase before thrombectomy for ischemic stroke. N Engl J Med. 2018;378:1573–1582. - PubMed
    1. Smith EE, Saver JL, Cox M, Liang L, Matsouaka R, Xian Y, et al. Increase in endovascular therapy in get with the guidelines-stroke after the publication of pivotal trials. Circulation. 2017;136:2303–2310. - PubMed
    1. Parsons M, Spratt N, Bivard A, Campbell B, Chung K, Miteff F, et al. A randomized trial of tenecteplase versus alteplase for acute ischemic stroke. N Engl J Med. 2012;366:1099–1107. - PubMed
    1. Huang X, Cheripelli BK, Lloyd SM, Kalladka D, Moreton FC, Siddiqui A, et al. Alteplase versus tenecteplase for thrombolysis after ischaemic stroke (attest): a phase 2, randomised, open-label, blinded endpoint study. Lancet Neurol. 2015;14:368–376. - PubMed
    1. Seners P, Turc G, Maïer B, Mas JL, Oppenheim C, Baron JC. Incidence and predictors of early recanalization after intravenous thrombolysis: a systematic review and meta-analysis. Stroke. 2016;47:2409–2412. - PubMed

LinkOut - more resources