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Review
. 2018 Winter;18(4):339-344.
doi: 10.31486/toj.18.0040.

Oral Development and Pathology

Affiliations
Review

Oral Development and Pathology

Melinda B Clark et al. Ochsner J. 2018 Winter.

Abstract

Background: The mouth is integral in the development of feeding, the initiation of digestion, and for speech and socialization. Signs of systemic disease and nutritional deficiencies often manifest in the mouth, and poor oral health can exacerbate many systemic conditions.

Methods: This review addresses the fetal development of the mouth, major anomalies, common minor physical findings, and pathologic conditions and their management.

Results: Pediatric practitioners have historically been poorly trained in diagnosis and management of oral conditions, so this article provides an overview of oral embryology and pathology, with a focus on hard and soft tissue disease identification, triage, and management. For primary prevention to be effective, pediatric providers must be knowledgeable about the process of dental caries, prevention of the disease, and available interventions, including fluoride.

Conclusion: The embryology and anatomy of the oral cavity are complex, and the mouth is crucial to many physiologic processes. Pediatric primary care providers are uniquely positioned to prevent, identify, and triage dental caries, the most common chronic disease of childhood.

Keywords: Abnormalities–mouth; dental caries; odontogenesis; pathology–oral.

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Figures

Figure 1.
Figure 1.. Mucous cleft palate.
Figure 2.
Figure 2.. Bilateral cleft lip and palate.
Figure 3.
Figure 3.. Trisomy 13 protruding cleft lip.
Figure 4.
Figure 4.. Bohn nodules.
Figure 5.
Figure 5.. Natal tooth.

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References

    1. Department of Health and Human Services Oral health in America: a report of the surgeon general. Rockville, MD: National Institute of Dental and Craniofacial Research, National Institutes of Health; 2000. https://profiles.nlm.nih.gov/ps/access/NNBBJT.pdf. Accessed September5, 2018.
    1. Moore LM, Persaud TVN. The Developing Human: Clinically Oriented Embryology. 8th ed. Philadelphia, PA: Saunders; 2008.
    1. Mai CT, Cassell CH, Meyer RE,et al. ; National Birth Defects Prevention Network. Birth defects data from population-based birth defects surveillance programs in the United States, 2007-2011: highlighting orofacial clefts. Birth Defects Res A Clin Mol Teratol. 2014. November;100(11):895-904. doi: 10.1002/bdra.23329. - DOI - PMC - PubMed
    1. Canfield MA, Honein MA, Yuskiv N,et al. . National estimates and race/ethnic-specific variation of selected birth defects in the United States, 1999-2001. Birth Defects Res A Clin Mol Teratol. 2006. November;76(11):747-756. - PubMed
    1. Chevrier C, Dananché B, Bahuau M,et al. . Occupational exposure to organic solvent mixtures during pregnancy and the risk of non-syndromic oral clefts. Occup Environ Med. 2006. September;63(9):617-623. - PMC - PubMed

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