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. 2019 Oct;31(10):1525-1529.
doi: 10.1007/s40520-018-1094-7. Epub 2018 Dec 17.

Influence of bone densitometry on the anti-osteoporosis treatment after fragility hip fracture

Peiwen Wang  1 , Yizhong Li  2 , Huafeng Zhuang  1 , Haiming Yu  1 , Siqing Cai  3 , Hao Xu  1 , Zhenhui Chen  1 , Jinkuang Lin  1 , Xuedong Yao  1
Affiliations

Influence of bone densitometry on the anti-osteoporosis treatment after fragility hip fracture

Peiwen Wang et al. Aging Clin Exp Res. 2019 Oct.

Abstract

Background: Fragility fracture significantly increases risk of future fracture. The fragility fracture cycle should be disrupted. The secondary fracture prevention is important for the patients with fragility hip fracture. The pharmacotherapy for osteoporosis is important for prevention of new fracture. However, many patients with hip fracture do not receive osteoporosis treatment. This retrospective study investigates the influence of bone mineral density (BMD) assessment on the initiation of anti-osteoporosis medications in the hospitalized patients with fragility hip fracture.

Methods: This retrospective research enrolled 1211 patients with fragility hip fracture 50 years of age and older. Among 1211 patients aged from 50 to 103 years with the average age of 77.83 ± 9.95 years, there were 807 females and 404 males. There were 634 fractures of femoral neck and 577 intertrochanteric fractures of femur. We examined whether patients had received bone mineral density assessment and received anti-osteoporosis therapy during the period of hospitalization. The patients were divided into BMD assessment group and no BMD assessment group. Measurement data were expressed as mean ± standard deviation and compared with t test. All parameters of groups were compared with Chi-square test.

Results: Of 1211 patients, 331 (27.33%) had received BMD assessment and 925 (76.38%) had received anti-osteoporosis drugs during the period of hospitalization. The rate of bisphosphonate use was lower and only 11.31% in the total patients. The anti-osteoporosis treatment rate was 93.66% in the patients receiving BMD assessment and 69.89% in the patients without BMD assessment (p < 0.01). The zoledronate use significantly increased from 6.7% in the patients without BMD assessment to 23.56% in the patients receiving BMD assessment (p < 0.01).

Conclusions: BMD assessment is a good basis for communication between patients and orthopedic surgeons. BMD assessment significantly increases the initiation of osteoporosis treatment and bisphosphonate use in the patients with hip fracture during the period of hospitalization.

Keywords: Bone mineral density assessment; Hip fracture; Osteoporosis; Treatment.

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Conflict of interest statement

The authors declare that they have no competing interests.

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