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. 1978 Dec;24(6):650-3.
doi: 10.1002/cpt1978246650.

Serum and urine phosphate during short-term beta-adrenergic blockade in healthy men

Serum and urine phosphate during short-term beta-adrenergic blockade in healthy men

R Lindsay et al. Clin Pharmacol Ther. 1978 Dec.

Abstract

Treatment of 6 healthy adult men with a beta-blocker, timolol, resulted in a rise in serum phosphate which was maintained for the 5 days of therapy. This rise was accompanied by a transient fall in urine phosphate and a rise in the tubular maximum for phosphate reabsorption per unit glomerular filtration rate (TmPO4/GFR). No change in circulating parathyroid hormone or growth hormone could be demonstrated.

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