Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2019 Jan 8;116(2):347-349.
doi: 10.1073/pnas.1819948116. Epub 2018 Dec 18.

A ray of light for treating cardiac conduction disorders

Affiliations
Comment

A ray of light for treating cardiac conduction disorders

Ron Feiner et al. Proc Natl Acad Sci U S A. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Schematic illustration depicting the stimulation of a whole heart using the polymer–SiNW mesh. The mesh is placed onto the heart, and a microscope objective (Obj) is used to irradiate it. The beating motions of the heart move it in and out of focus, thus exposing the cells only to intermittent laser radiation each time, similar to the effect achieved with the scanning laser used on cultured cells. ECG electrodes were placed on the heart to monitor its response to the laser-induced pacing.

Comment on

References

    1. Feiner R, Dvir T. Tissue–electronics interfaces: From implantable devices to engineered tissues. Nat Rev Mater. 2017;3:17076.
    1. Berthelsen WA. 1990. Screw-in drug eluting lead. US Patent 4,953,564.
    1. Parameswaran R, et al. Optical stimulation of cardiac cells with a polymer-supported silicon nanowire matrix. Proc Natl Acad Sci USA. 2019;116:413–421. - PMC - PubMed
    1. Nussinovitch U, Gepstein L. Optogenetics for in vivo cardiac pacing and resynchronization therapies. Nat Biotechnol. 2015;33:750–754. - PubMed
    1. Gentemann L, et al. Modulation of cardiomyocyte activity using pulsed laser irradiated gold nanoparticles. Biomed Opt Express. 2016;8:177–192. - PMC - PubMed

LinkOut - more resources