2018 WSES/SIS-E consensus conference: recommendations for the management of skin and soft-tissue infections

Massimo Sartelli¹, Xavier Guirao², Timothy C Hardcastle³, Yoram Kluger⁴, Marja A Boermeester⁵, Kemal Raşa⁶, Luca Ansaloni⁷, Federico Coccolini⁷, Philippe Montravers⁸, Fikri M Abu-Zidan⁹, Michele Bartoletti¹⁰, Matteo Bassetti¹¹, Offir Ben-Ishay⁴, Walter L Biffl¹², Osvaldo Chiara¹³, Massimo Chiarugi¹⁴, Raul Coimbra¹⁵, Francesco Giuseppe De Rosa¹⁶, Belinda De Simone¹⁷, Salomone Di Saverio¹⁸, Maddalena Giannella¹⁰, George Gkiokas¹⁹, Vladimir Khokha²⁰, Francesco M Labricciosa²¹, Ari Leppäniemi²², Andrey Litvin²³, Ernest E Moore²⁴, Ionut Negoi²⁵, Leonardo Pagani²⁶, Maddalena Peghin¹¹, Edoardo Picetti²⁷, Tadeja Pintar²⁸, Guntars Pupelis²⁹, Ines Rubio-Perez³⁰, Boris Sakakushev³¹, Helmut Segovia-Lohse³², Gabriele Sganga³³, Vishal Shelat³⁴, Michael Sugrue³⁵, Antonio Tarasconi³⁶, Cristian Tranà¹, Jan Ulrych³⁷, Pierluigi Viale¹⁰, Fausto Catena³³

Affiliations

¹ Department of Surgery, Macerata Hospital, Macerata, Italy.
² 2Unit of Endocrine, Head, and Neck Surgery and Unit of Surgical Infections Support, Department of General Surgery, Parc Taulí Hospital Universitari, Sabadell, Spain.
³ Trauma Service, Inkosi Albert Luthuli Central Hospital and Department of Surgery, Nelson R Mandela School of Clinical Medicine, Durban, South Africa.
⁴ 4Department of General Surgery, Division of Surgery, Rambam Health Care Campus, Haifa, Israel.
⁵ 5Department of Surgery, Academic Medical Centre, Amsterdam, Netherlands.
⁶ Department of Surgery, Anadolu Medical Center, Kocaali, Turkey.
⁷ 7General Surgery Department, Bufalini Hospital, Cesena, Italy.
⁸ 8Anesthesiology and Critical Care Medicine, Paris Diderot Sorbonne Cite University, Bichat-Claude Bernard University Hospital, HUPNSV, Paris, France.
⁹ 9Department of Surgery, College of Medicine and Health Sciences, UAE University, Al-Ain, United Arab Emirates.
¹⁰ 10Infectious Diseases Unit, Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.
¹¹ 11Infectious Diseases Division, Department of Medicine University of Udine and Azienda Sanitaria Universitaria Intergrata di Udine, Udine, Italy.
¹² Trauma and Acute Care Surgery, Scripps Memorial Hospital La Jolla, La Jolla, CA USA.
¹³ General Surgery-Trauma Team, State University of Milano, Niguarda Hospital Milano, Milan, Italy.
¹⁴ 14Emergency Surgery Unit, State University of Pisa, Cisanello Hospital, Pisa, Italy.
¹⁵ 15Riverside University Health System Medical Center and Loma Linda University School of Medicine, Moreno Valley, CA USA.
¹⁶ 16Department of Medical Sciences, Infectious Diseases, University of Turin, Turin, Italy.
¹⁷ Unit of General, Emergency and Trauma Surgery, Regional Hospital of Perpignan, Perpignan, France.
¹⁸ 18Department of Surgery, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
¹⁹ 19Second Department of Surgery, Aretaieion University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
²⁰ Department of Emergency Surgery, City Hospital, Mozyr, Belarus.
²¹ Global Alliance for Infections in Surgery, Porto, Portugal.
²² Abdominal Center, University Hospital Meilahti, Helsinki, Finland.
²³ 23Department of Surgical Disciplines, Immanuel Kant Baltic Federal University, Regional Clinical Hospital, Kaliningrad, Russian Federation.
²⁴ Department of Surgery, University of Colorado, Denver Health Medical Center, Denver, CO USA.
²⁵ Department of Surgery, Emergency Hospital of Bucharest, Bucharest, Romania.
²⁶ Infectious Diseases Unit, Bolzano Central Hospital, Bolzano, Italy.
²⁷ 27Department of Anesthesia and Intensive Care, Azienda Ospedaliero-Universitaria Parma, Parma, Italy.
²⁸ 28Department of Surgery, UMC Ljubljana, Ljubljana, Slovenia.
²⁹ 29Department of General and Emergency Surgery, Riga East University Hospital 'Gailezers', Riga, Latvia.
³⁰ 30General Surgery Department, Colorectal Surgery Unit, La Paz University Hospital, Madrid, Spain.
³¹ 31General Surgery Department, Medical University, University Hospital St George, Plovdiv, Bulgaria.
³² 32Second Department of Surgery, Hospital de Clínicas, Universidad Nacional de Asuncion, San Lorenzo, Paraguay.
³³ 33Emergency Surgery (or Division of Emergency Surgery), Fondazione Policlinico Universitario A. Gemelli IRCCS - Università Cattolica del Sacro Cuore, Rome, Italy.
³⁴ 34General Surgery, Tan Tock Seng Hospital, Singapore, Singapore.
³⁵ 35Department of Surgery, Letterkenny University Hospital and Donegal Clinical Research Academy, Letterkenny, Ireland.
³⁶ Department of Emergency Surgery, Parma Maggiore Hospital, Parma, Italy.
³⁷ 37First Department of Surgery, Department of Abdominal, Thoracic Surgery and Traumatology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.

PMID: 30564282
PMCID: PMC6295010
DOI: 10.1186/s13017-018-0219-9

Review

2018 WSES/SIS-E consensus conference: recommendations for the management of skin and soft-tissue infections

Massimo Sartelli et al. World J Emerg Surg. 2018.

. 2018 Dec 14:13:58.

doi: 10.1186/s13017-018-0219-9. eCollection 2018.

Authors

Affiliations

¹ Department of Surgery, Macerata Hospital, Macerata, Italy.
² 2Unit of Endocrine, Head, and Neck Surgery and Unit of Surgical Infections Support, Department of General Surgery, Parc Taulí Hospital Universitari, Sabadell, Spain.
³ Trauma Service, Inkosi Albert Luthuli Central Hospital and Department of Surgery, Nelson R Mandela School of Clinical Medicine, Durban, South Africa.
⁴ 4Department of General Surgery, Division of Surgery, Rambam Health Care Campus, Haifa, Israel.
⁵ 5Department of Surgery, Academic Medical Centre, Amsterdam, Netherlands.
⁶ Department of Surgery, Anadolu Medical Center, Kocaali, Turkey.
⁷ 7General Surgery Department, Bufalini Hospital, Cesena, Italy.
⁸ 8Anesthesiology and Critical Care Medicine, Paris Diderot Sorbonne Cite University, Bichat-Claude Bernard University Hospital, HUPNSV, Paris, France.
⁹ 9Department of Surgery, College of Medicine and Health Sciences, UAE University, Al-Ain, United Arab Emirates.
¹⁰ 10Infectious Diseases Unit, Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.
¹¹ 11Infectious Diseases Division, Department of Medicine University of Udine and Azienda Sanitaria Universitaria Intergrata di Udine, Udine, Italy.
¹² Trauma and Acute Care Surgery, Scripps Memorial Hospital La Jolla, La Jolla, CA USA.
¹³ General Surgery-Trauma Team, State University of Milano, Niguarda Hospital Milano, Milan, Italy.
¹⁴ 14Emergency Surgery Unit, State University of Pisa, Cisanello Hospital, Pisa, Italy.
¹⁵ 15Riverside University Health System Medical Center and Loma Linda University School of Medicine, Moreno Valley, CA USA.
¹⁶ 16Department of Medical Sciences, Infectious Diseases, University of Turin, Turin, Italy.
¹⁷ Unit of General, Emergency and Trauma Surgery, Regional Hospital of Perpignan, Perpignan, France.
¹⁸ 18Department of Surgery, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
¹⁹ 19Second Department of Surgery, Aretaieion University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
²⁰ Department of Emergency Surgery, City Hospital, Mozyr, Belarus.
²¹ Global Alliance for Infections in Surgery, Porto, Portugal.
²² Abdominal Center, University Hospital Meilahti, Helsinki, Finland.
²³ 23Department of Surgical Disciplines, Immanuel Kant Baltic Federal University, Regional Clinical Hospital, Kaliningrad, Russian Federation.
²⁴ Department of Surgery, University of Colorado, Denver Health Medical Center, Denver, CO USA.
²⁵ Department of Surgery, Emergency Hospital of Bucharest, Bucharest, Romania.
²⁶ Infectious Diseases Unit, Bolzano Central Hospital, Bolzano, Italy.
²⁷ 27Department of Anesthesia and Intensive Care, Azienda Ospedaliero-Universitaria Parma, Parma, Italy.
²⁸ 28Department of Surgery, UMC Ljubljana, Ljubljana, Slovenia.
²⁹ 29Department of General and Emergency Surgery, Riga East University Hospital 'Gailezers', Riga, Latvia.
³⁰ 30General Surgery Department, Colorectal Surgery Unit, La Paz University Hospital, Madrid, Spain.
³¹ 31General Surgery Department, Medical University, University Hospital St George, Plovdiv, Bulgaria.
³² 32Second Department of Surgery, Hospital de Clínicas, Universidad Nacional de Asuncion, San Lorenzo, Paraguay.
³³ 33Emergency Surgery (or Division of Emergency Surgery), Fondazione Policlinico Universitario A. Gemelli IRCCS - Università Cattolica del Sacro Cuore, Rome, Italy.
³⁴ 34General Surgery, Tan Tock Seng Hospital, Singapore, Singapore.
³⁵ 35Department of Surgery, Letterkenny University Hospital and Donegal Clinical Research Academy, Letterkenny, Ireland.
³⁶ Department of Emergency Surgery, Parma Maggiore Hospital, Parma, Italy.
³⁷ 37First Department of Surgery, Department of Abdominal, Thoracic Surgery and Traumatology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.

PMID: 30564282
PMCID: PMC6295010
DOI: 10.1186/s13017-018-0219-9

Abstract

Skin and soft-tissue infections (SSTIs) encompass a variety of pathological conditions that involve the skin and underlying subcutaneous tissue, fascia, or muscle, ranging from simple superficial infections to severe necrotizing infections. SSTIs are a frequent clinical problem in surgical departments. In order to clarify key issues in the management of SSTIs, a task force of experts met in Bertinoro, Italy, on June 28, 2018, for a specialist multidisciplinary consensus conference under the auspices of the World Society of Emergency Surgery (WSES) and the Surgical Infection Society Europe (SIS-E). The multifaceted nature of these infections has led to a collaboration among general and emergency surgeons, intensivists, and infectious disease specialists, who have shared these clinical practice recommendations.

Keywords: Necrotizing infection; Soft-tissue infections; Surgical site infection.

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Conflict of interest statement

Not applicable.Not applicable.In the past 5 years, MB has participated in advisory boards and/or received speaker honoraria from Achaogen, Angelini, Astellas, AstraZeneca, Bayer, Basilea, Cidara, Gilead, Melinta, Menarini, MSD, Nabriva, Paratek, Pfizer, Roche, The Medicine Company, Shionogi, Tetraphase, VenatoRX, and Vifor. All other authors declared no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

References

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2018 WSES/SIS-E consensus conference: recommendations for the management of skin and soft-tissue infections

Affiliations

2018 WSES/SIS-E consensus conference: recommendations for the management of skin and soft-tissue infections

Authors

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Abstract

Conflict of interest statement

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