Neutrophils Stepping Through (to the Other Side)
- PMID: 30566887
- DOI: 10.1016/j.immuni.2018.12.006
Neutrophils Stepping Through (to the Other Side)
Abstract
The neutrophil's journey through the vascular wall constitutes a critical step during inflammation. In this issue of Immunity, Girbl et al. (2018) demonstrate that neutrophil extravasation is mediated by sequential and compartmentalized chemokine action, endowing unexpected specificity to promiscuous chemokine receptors.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
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Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis.Immunity. 2018 Dec 18;49(6):1062-1076.e6. doi: 10.1016/j.immuni.2018.09.018. Epub 2018 Nov 13. Immunity. 2018. PMID: 30446388 Free PMC article.
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