High altitude area - A risk factor for gastric perforation? : A case series
- PMID: 30567061
- PMCID: PMC6262768
- DOI: 10.1016/j.ijscr.2018.11.037
High altitude area - A risk factor for gastric perforation? : A case series
Abstract
Introduction: This is an original case series on soldiers evacuated from HAA(High Altitude Area) over last one year(Sept 2017-Aug 2018), of which 100% cases were found to have gastric antrum perforation. This is a deviation from the usual trend that is being noted in Indian subcontinent where duodenal perforations are commonest.
Discussion: High altitude associated dyspepsia is a common phenomenon and some studies done in high altitude population have recorded high incidence of antral gastritis and mucosal atrophy on histo-pathological evaluation. This is also supported by high incidence of H. pylori infection. The presence of atrophic gastric mucosa associated with antral gastritis, when exposed to hypobaric hypoxemic conditions faced by soldiers posted to heights above 15,000 ft, may leads to increased intra-luminal pressure and ischemia which probably predisposes individuals for gastric antrum perforations.
Conclusion: This is a relatively untouched topic as we have not found studies onhigh altitude related gastric perforations and probably this is the first case series of its kind. The acknowledgement of this phenomenon may pave way for further studies for defining the role of high altitude in gastric perforations.
Keywords: Gastric antrum; High altitude; Intra-luminal pressure; Mucosal atrophy; Perforations.
Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.
Figures
References
-
- Agha RiazA., Fowler Alexander J., Rajmohan Shivanchan, Barai Ishani, Orgill Dennis P., for the PROCESS Group Preferred reporting of case series in surgery; the PROCESS guidelines. Int. J. Surg. 2016 - PubMed
-
- Agha RiazA., Fowler Alexander J., Rajmohan Shivanchan, Barai Ishani, Orgill Dennis P., for the PROCESS Group Preferred reporting of case series in surgery; the PROCESS guidelines. Int. J. Surg. 2016 - PubMed
-
- Moller M.H., Adamsen S., Thomsen R.W. Multicentre trial of a perioperative protocol to reduce mortality in patients with peptic ulcer perforation. Br. J. Surg. 2011;98(6):802–810. [PubMed] - PubMed
-
- Svanes C., Lie R.T., Kvåle G., Svanes K., Søreide O. Incidence of perforated ulcer in western Norway 1935–1990: cohort or period dependent time trends? Am. J. Epidemiol. 1995;141:836. - PubMed
-
- Coggon D., Lambert P., Langman M.J.S. 20 years of hospital admissions for peptic ulcer in England and Wales. Lancet. 1981;1:1302. - PubMed
LinkOut - more resources
Full Text Sources