Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Nov-Dec;18(6):356-362.
doi: 10.5698/1535-7597.18.6.356.

Genetics of Focal Epilepsies: What Do We Know and Where Are We Heading?

Affiliations

Genetics of Focal Epilepsies: What Do We Know and Where Are We Heading?

Piero Perucca. Epilepsy Curr. 2018 Nov-Dec.

Abstract

This article is based on a lecture delivered at the 2017 American Epilepsy Society Annual Meeting and provides an overview of the growing evidence supporting the strong genetic contribution to focal epilepsies. This also discusses how advances in the molecular genetics of focal epilepsies are rapidly translating to routine clinical care.

PubMed Disclaimer

References

    1. Devinsky O, Vezzani A, O'Brien TJ, Jette N, Scheffer IE, de Curtis M, Perucca P. Epilepsy. Nat Rev Dis Primers. 2018;4 18024. - PubMed
    1. Ottman R. Progress in the genetics of the partial epilepsies. Epilepsia. 2001;42(suppl 5):24–30. - PMC - PubMed
    1. Thomas RH, Berkovic SF. The hidden genetics of epilepsy – a clinically important new paradigm. Nat Rev Neurol. 2014;10:283–292. - PubMed
    1. Zimmerman R, Pal DK, Tin A, Ahsan H, Greenberg DA. Methods for assessing familial aggregation: family history measures and confounding in the standard cohort, reconstructed cohort and case-control designs. Hum Hered. 2009;68:201–208. - PMC - PubMed
    1. Peljto AL, Barker-Cummings C, Vasoli VM, Leibson CL, Hauser WA, Buchhalter JR, Ottman R. Familial risk of epilepsy: a population-based study. Brain. 2014;137(pt 3):795–805. - PMC - PubMed

LinkOut - more resources