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. 2018 Dec 15;32(12):1560-1566.
doi: 10.7507/1002-1892.201807026.

[Vertebral three-dimensional motion characteristics of adjacent segments in patients with isthmic spondylolisthesis in vivo]

[Article in Chinese]
Hongda Xu  1 , Jianan Liu  1 , Hongda Li  2 , Dong Wei  2 , Jun Miao  3 , Qun Xia  2
Affiliations

[Vertebral three-dimensional motion characteristics of adjacent segments in patients with isthmic spondylolisthesis in vivo]

[Article in Chinese]
Hongda Xu et al. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. .

Abstract
in English, Chinese

Objective: To observe vertebral three-dimensional motion characteristics of adjacent segments in patients with symptomatic L 4 isthmic spondylolisthesis (IS).

Methods: Fourteen symptomatic L 4 IS patients who underwent surgery treatment (trial group) and 15 asymptomatic volunteers without back pain and other lesions of spine (control group) were recruited. There was no significant difference in gender, age, body mass index, and bone mineral density between the two groups ( P>0.05). The three-dimensional reconstruction model of lumbar spine was acquired from the thin slice CT of the lumbar spine of the subjects by combining dual-X-ray fluoroscopy imaging system with spiral CT examination. The model was matched to the double oblique X-ray fluoroscopy images captured by dual-X-ray fluoroscopy imaging system at different active positions of the lumbar spine to reproduce the three-dimensional instantaneous of lumbar spondylolisthesis at different state of motion. The motion and relative displacement of adjacent segments (L 3, 4 and L 5, S 1) of spondylolisthesis were measured quantitatively by establishing a three-dimensional coordinate system at the geometric center of the vertebral body. The results were compared with those of the control group.

Results: When L 3, 4 in the control group were flexed flexion-extension, left-right twisting, and left-right bending, and when L 5, S 1 in the control group were flexed left-right twisting and left-right bending, the activity along the main axis of motion (main axis of motion) tended to increase compared with that along the corresponding coupled axis of motion (secondary axis of motion); however, this trend disappeared in the trial group, and the main and secondary movements were disordered. Because of the coronal orientation of the facet joints of L 5, S 1, the degree of motion along the main axis of motion decreased during flexion and extension, but this trend disappeared in the trial group. Compared with the control group, L 3, 4 in the trial group exhibited displacement instability in flexion-extension, left-right twisting, and left-right bending ( P<0.05); there was no significant difference in the relative displacement of L 5, S 1 intervertebral bodies along x, y, and z axes between the trial group and the control group in flexion-extension, left-right twisting, and left-right bending curvature ( P>0.05).

Conclusion: Patients with symptomatic L 4 IS have disorders of primary and secondary movement patterns in adjacent segments, while IS showed significantly displacement instability in L 3, 4 and significantly decreased motion in L 5, S 1.

目的: 探讨有临床症状的腰椎峡部裂滑脱（isthmic spondylolisthesis，IS）患者生理载荷下相邻节段三维瞬时运动特征。.

方法: 选取有临床症状需手术治疗的 L 4 IS 患者 14 例为研究组；以 15 名无腰痛症状和脊柱疾病的健康志愿者为对照组。两组受试者性别、年龄、体质量指数、骨密度比较，差异均无统计学意义（ P>0.05），具有可比性。采用双 X 线透视影像系统和螺旋 CT 检查结合技术，从受试者腰椎薄层 CT 获取腰椎三维重建模型，匹配到由双 X 线透视影像系统捕获的不同活动体位时腰椎双斜位 X 线透视图像上，重现生理载荷下不同活动体位腰椎滑脱节段三维瞬时运动状态。通过在椎体几何中心建立三维坐标系测量相邻节段（L 3、 4 和 L 5、S 1）椎体间的活动度和相对位移，并与对照组比较。.

结果: 对照组 L 3、 4 在前屈-后伸、左旋-右旋和左侧弯-右侧弯时，L 5、S 1 在左旋-右旋和左侧弯-右侧弯时，沿主要运动轴（主运动轴）的活动度均较相应耦合运动轴（次运动轴）活动度有增大趋势；但研究组这种趋势消失，主次运动紊乱。L 5、S 1 由于椎间小关节方向偏冠状位，前屈-后伸时沿主要运动轴活动度较相应耦合运动轴活动度变小；但研究组这种趋势消失。与对照组相比，研究组 L 3、 4 在前屈-后伸、左侧弯-右侧弯和左旋-右旋时存在位移失稳（ P<0.05）；研究组 L 5、S 1 椎体间在前屈-后伸、左旋-右旋和左侧弯-右侧弯时沿 x、y、z 轴的相对位移与对照组比较，差异均无统计学意义（ P>0.05）。.

结论: 有临床症状的 L 4 IS 患者相邻节段主次运动模式紊乱，且相邻头侧椎间运动存在位移失稳，而尾侧椎间运动趋于稳定。.

Keywords: Lumbar spine; isthmic spondylolisthesis; kinematics; spinal surgery.

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Figures

图 1
图 1
Dual-X-ray fluoroscopy imaging system 双 X 线影像透视系统
图 2
图 2
Establishment of three-dimensional coordinate system in vertebral body geometry center 在椎体几何中心建立三维坐标系
图 3
图 3
Adjacent segment mobility of L4 IS L4 IS 相邻节段活动度
图 4
图 4
Relative displacement of adjacent segments of L4 IS L4 IS 相邻节段相对位移
See this image and copyright information in PMC

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