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Review
. 2018 Dec;49(12):3107-3114.
doi: 10.1161/STROKEAHA.118.021359.

New Directions in Treatments Targeting Stroke Recovery

David J Lin  1 , Seth P Finklestein  2 , Steven C Cramer  3
Affiliations
Review

New Directions in Treatments Targeting Stroke Recovery

David J Lin et al. Stroke. 2018 Dec.
No abstract available

Keywords: brain; clinical trials; rehabilitation; stroke; therapeutics.

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Figures

Figure 1.
Figure 1.
Summary of current experimental treatments for stroke recovery and their readiness for incorporation into clinical practice based on synthesis of current evidence. Readiness for clinical application ranges from preclinical development (i.e. in animal studies only, red) to broad clinical application (green).
See this image and copyright information in PMC

References

    1. Bernhardt J, Hayward KS, Kwakkel G, Ward NS, Wolf SL, Borschmann K, et al. Agreed definitions and a shared vision for new standards in stroke recovery research: The stroke recovery and rehabilitation roundtable taskforce. Int J Stroke. 2017;12:444–450 - PubMed
    1. Dobkin BH, Carmichael ST. The specific requirements of neural repair trials for stroke. Neurorehabilitation and Neural Repair. 2016;30:470–478 - PMC - PubMed
    1. Cramer SC, Koroshetz WJ, Finklestein SP. The case for modality-specific outcome measures in clinical trials of stroke recovery-promoting agents. Stroke. 2007;38:1393–1395 - PubMed
    1. Cramer SC, Wolf SL, Adams HP Jr., Chen D, Dromerick AW, Dunning K, et al. Stroke recovery and rehabilitation research: Issues, opportunities, and the National Institutes of Health StrokeNet. Stroke. 2017;48:813–819 - PMC - PubMed
    1. Pollock A, Farmer SE, Brady MC, Langhorne P, Mead GE, Mehrholz J, et al. Interventions for improving upper limb function after stroke. Cochrane database systematic reviews. 2014;11:CD010820-CD010820 - PMC - PubMed

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