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Case Reports
. 2019 Jan;67(1):128-129.
doi: 10.4103/ijo.IJO_867_18.

Multimodal imaging characteristics of refractile drusen

Affiliations
Case Reports

Multimodal imaging characteristics of refractile drusen

Samarth Mishra et al. Indian J Ophthalmol. 2019 Jan.
No abstract available

Keywords: Calcified drusen; drusen; ossified drusen; refractile drusen.

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Conflict of interest statement

None

Figures

Figure 1
Figure 1
(a) Color fundus photograph of the right eye showing refractile drusen as yellow, glistening deposits in the macular and perimacular area (thick white arrow), and soft drusen circumferentially (thin white arrow) with an area of central retinal pigment epithelium atrophy (arrowhead). Hyper-reflectant structure seen superonasal to the fovea is artifactual (black arrow). (b) Multicolor composite image highlights the refractile drusen as small, yellow, glistening deposits (thick white arrow), whereas the soft drusen appears as green with an orange border (thin white arrow). (c and d) Magnified conventional fundus photography and multicolor composite image view of refractile drusen (thick white arrow), soft drusen (thin white arrow), and artifact (black arrow)
Figure 2
Figure 2
(a and b) Spectral domain optical coherence tomography scan of the right eye passing through the refractile drusen (thick white arrow in the optical coherence tomography scan), with significant back shadowing. Soft drusen (thin white arrow) appears as bumpy elevations in the optical coherence tomography with uniform hyper-reflective material inside without any back shadowing
Figure 3
Figure 3
(a and b) Near-infrared autofluorescence (a) and blue autofluorescence (b) highlight the area of retinal pigment epithelium atrophy. (c) Infrared reflectance fails to highlight the drusen. (d) Blue reflectance image shows refractile drusen as hyper-reflectant lesions (thick white arrow). Soft drusen appears mildly hyper-reflectant with surrounding dark borders (thin white arrow). Arrowhead shows the area of retinal pigment epithelium atrophy. (e) Green reflectance image distinctly highlights the refractile drusen as hyper-reflectant material (thick white arrow), whereas soft drusen as mildly hyper-reflectant with dark borders (thin white arrow) surrounding it with distinct retinal pigment epithelium atrophic area (arrowheads)

References

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