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Review
. 2019 Dec;219(9):505-513.
doi: 10.1016/j.rce.2018.10.006. Epub 2018 Dec 19.

Laboratory guidelines for the diagnosis of patients with cryoglobulinaemic syndrome

[Article in English, Spanish]
A Mariscal-Rodríguez  1 , L M Villar Guimerans  2 , M López-Trascasa  3 , M Hernández González  4 , E Moga Naranjo  5 ; en nombre del grupo de inmunoquímica de la Sociedad Española de Inmunología
Affiliations
Review

Laboratory guidelines for the diagnosis of patients with cryoglobulinaemic syndrome

[Article in English, Spanish]
A Mariscal-Rodríguez et al. Rev Clin Esp (Barc). 2019 Dec.

Abstract

Cryoglobulinaemic syndromes include a collection of manifestations that are found in various diseases and that share a pathophysiological mechanism: cryoglobulin deposit in vascular beds. For these syndromes, the presence of cryoglobulins is a diagnostic criterion, and their correct detection and characterisation are therefore essential. The Immunochemistry Group of the Spanish Society of Immunology conducted a comprehensive clinical and methodological review, due to the interlaboratory heterogeneity in techniques, with the objective of providing a useful and effective tool for diagnosing cryoglobulinaemic syndromes.

Keywords: Crioglobulinas; Cryoglobulinaemic syndromes; Cryoglobulins; Síndromes crioglobulinémicos; Vasculitis.

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