Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Jun;37(6):592-603.
doi: 10.1016/j.tibtech.2018.11.013. Epub 2018 Dec 22.

Tackling Cancer with Yeast-Based Technologies

Raphael Ferreira  1 , Angelo Limeta  2 , Jens Nielsen  3
Affiliations
Review

Tackling Cancer with Yeast-Based Technologies

Raphael Ferreira et al. Trends Biotechnol. 2019 Jun.

Abstract

The ability to precisely engineer yeast, coupled with its genetic and metabolic similarity to tumor cells, has enabled researchers to use this organism in cancer research. Here we review advances that leveraged yeast as a model organism for studying cancer biology, including the investigation of tumorigenic mechanisms, development of advanced technologies for drug discovery, production of anticancer drugs on an industrial scale, and delivering the next generation of immunotherapies.

Keywords: CRISPR; SGA; cancer vaccines; humanized antibody; immunotherapy; metabolic engineering.

PubMed Disclaimer

Publication types

Substances

LinkOut - more resources