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Clinical Trial
. 1988 Sep-Oct;16(5):338-48.
doi: 10.1177/030006058801600503.

Analgesic activity of flupirtine maleate: a controlled double-blind study with diclofenac sodium in orthopaedics

P Mastronardi  1 , M D'Onofrio, E Scanni, M Pinto, S Frontespezi, M G Ceccarelli, F Bianchi, B Mazzarella
Affiliations
Clinical Trial

Analgesic activity of flupirtine maleate: a controlled double-blind study with diclofenac sodium in orthopaedics

P Mastronardi et al. J Int Med Res. 1988 Sep-Oct.

Abstract

A controlled, parallel group study of the analgesic efficacy of flupirtine maleate, was compared against diclofenac sodium in 40 orthopaedic patients with post-operative pain. Clinically, both drugs were of equal analgesic efficacy. A mathematical model has been developed, however, to evaluate the speed, intensity and duration of the analgesic effect and provides data which significantly favour flupirtine maleate in the treatment of these patients.

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