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. 1978 Apr 15;34(4):528-30.
doi: 10.1007/BF01935971.

Effects of the antiprotease Trasylol on peripheral blood leucocytes

A W Thomson, R G Pugh-Humphreys, D J Tweedie, C H Horne

Effects of the antiprotease Trasylol on peripheral blood leucocytes

A W Thomson et al. Experientia. .

Abstract

Binding of the antiprotease Trasylol to human peripheral blood lymphocytes and polymorphonuclear leucocytes (PMNs) was demonstrated at the ultrastructural level using an indirect immunoperoxidase technique. This also revealed endocytosis of membrane bound Trasylol by PMNs. Trasylol inhibited PHA- and ConA-induced lymphocyte stimulation, and was cytotoxic to unstimulated cells.

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