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Multicenter Study
. 2019 Jan 8;8(1):e010324.
doi: 10.1161/JAHA.118.010324.

Sex Differences in Receiving Layperson Cardiopulmonary Resuscitation in Pediatric Out-of-Hospital Cardiac Arrest: A Nationwide Cohort Study in Japan

Masashi Okubo  1 , Tasuku Matsuyama  2 , Koichiro Gibo  3 , Sho Komukai  4 , Junichi Izawa  5   6 , Kosuke Kiyohara  7 , Chika Nishiyama  8 , Takeyuki Kiguchi  9 , Clifton W Callaway  1 , Taku Iwami  9 , Tetsuhisa Kitamura  10
Affiliations
Multicenter Study

Sex Differences in Receiving Layperson Cardiopulmonary Resuscitation in Pediatric Out-of-Hospital Cardiac Arrest: A Nationwide Cohort Study in Japan

Masashi Okubo et al. J Am Heart Assoc. .

Abstract

Background Layperson cardiopulmonary resuscitation ( CPR ) is a crucial intervention for patients with out-of-hospital cardiac arrest ( OHCA ). Although a sex disparity in receiving layperson CPR (ie, female patients were less likely to receive layperson CPR ) has been reported in adults, there are few data in the pediatric population, and we therefore investigated sex differences in receiving layperson CPR in pediatric patients with OHCA . Methods and Results From the All-Japan Utstein Registry, a prospective, nationwide, population-based OHCA database, we included pediatric patients (≤17 years) with layperson-witnessed OHCA from 2005 through 2015. The primary outcome was receiving layperson CPR . Patient sex was the main exposure. We fitted multivariable logistic regression models to examine associations between patient sex and receiving layperson CPR . We included a total of 4525 pediatric patients with layperson-witnessed OHCA in this study, 1669 (36.9%) of whom were female. Female patients received layperson CPR more often than male patients (831/1669 [49.8%] versus 1336/2856 [46.8%], P=0.05). After adjustment for age, time of day of arrest, year, witnesses persons, and dispatcher CPR instruction, the sex difference in receiving layperson CPR was not significant (adjusted odds ratio for female subjects 1.14, 95% CI, 0.996-1.31). Conclusions In a pediatric population, female patients with layperson-witnessed OHCA received layperson CPR more often than male patients. After adjustment for covariates, there was no significant association between patient sex and receiving layperson CPR .

Keywords: cardiac arrest; cardiopulmonary resuscitation; gender differences; pediatric.

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Figures

Figure 1
Figure 1
Study participant flowchart. CPR indicates cardiopulmonary resuscitation; EMS, emergency medical services.
Figure 2
Figure 2
Association between receiving layperson cardiopulmonary resuscitation and sex of the patient, stratified by age group. Overall layperson‐witnessed arrest (A), arrest witnessed by family (B), and arrest witnessed by nonfamily (C). *Adjusted for age group, time of day of arrest, year, witnesses, and dispatcher CPR instruction. †Adjusted for age group, time of day of arrest, year, and dispatcher CPR instruction. OR indicates odds ratio.
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