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. 2018 Sep 19:13:136-142.
doi: 10.1016/j.jbo.2018.09.004. eCollection 2018 Nov.

Evaluation of short-term efficacy of extraspinal cementoplasty for bone metastasis: A monocenter study of 31 patients

Gaëlle Couraud  1 , Gaston André-Pierre  2 , Tulier Titien  2 , Eymard Florent  1 , Hourdille Alexia  1 , Chevalier Xavier-Jean  1 , Hélene Boussion  3 , Guignard Sandra  1
Affiliations

Evaluation of short-term efficacy of extraspinal cementoplasty for bone metastasis: A monocenter study of 31 patients

Gaëlle Couraud et al. J Bone Oncol. .

Abstract

Objective: To study the effect on pain of per-cutaneous cementoplasty for painful extraspinal bone metastasis.

Method: 43 patients with extraspinal bone metastasis were included between April 2006 and October 2014 in this retrospective monocenter study. The primary endpoint was pain level measured on a 0-10 numeric rating scale at week 1 after cementoplasty as compared with pre-cementoplasty. Secondary endpoints were long-term pain level and impact on quality of life and disability.

Results: Mean pain score was 4.2 (SD ±3.6) before cementoplasty and 1.09 (SD ±2.4) at week 1 (p = 0.005) (n = 31 patients). At 22 months after cementoplasty, quality of life and disability improved (according to the patient global assessment) for 47.6% and 52.2% of patients (n = 21patients). We did not find a predictor of good response. Cement leakage was the most common adverse event.

Conclusion: Percutaneous cementoplasty of extraspinal bone metastasis is a rapidly efficient treatment with few adverse events. Its efficacy persists over time, with a benefit for disability and quality of life. Although this technique is only palliative, it should be considered in this situation.

Keywords: Bone metastasis; Pain management; Percutaneous cementoplasty.

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Figures

Fig 1
Fig. 1
(A). Bone metastasis of acetabulum (lung cancer). (B). Inflation of kyphopasty balloon with constrast product. (C). Cement injection after the baloon is deflated. (D). 3D Image.
Fig 2
Fig. 2
Flow chart.
See this image and copyright information in PMC

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