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. 2019:176:99-126.
doi: 10.1007/978-3-319-99716-2_5.

Angioimmunoblastic T-Cell Lymphoma

Mariko Yabe  1 , Ahmet Dogan  1 , Steven M Horwitz  2 , Alison J Moskowitz  3
Affiliations

Angioimmunoblastic T-Cell Lymphoma

Mariko Yabe et al. Cancer Treat Res. 2019.

Abstract

Angioimmunoblastic T-cell lymphoma (AITL) is one of the most common types of T-cell lymphoma, representing about 15-20% of cases of peripheral T-cell lymphoma (PTCL). It is characterized by a unique clinical presentation and distinct pathologic and molecular features. Classes of drugs particularly active in AITL are emerging; however, treatment of relapsed and refractory disease remains a challenge. This chapter reviews the epidemiology, clinical presentation, pathogenesis, diagnosis, and treatment of AITL.

Keywords: Angioimmunoblastic T-cell lymphoma; Follicular helper T-cell; Pathology; Treatment.

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