Review
[Histopathogenesis of goiters]
[Article in
French]
Affiliations
- PMID: 3059969
Item in Clipboard
Review
[Histopathogenesis of goiters]
[Article in
French]
Ann Endocrinol (Paris).
1988.
Abstract
The basic mechanisms acting in the transformation of a normal thyroid gland into a toxic or nontoxic goiter are summarized: 1) Any goiter arises from multiplication of follicular epithelial cells forming new follicles. 2) In the follicular epithelium there are cell families with much higher than average growth potential. 3) Cells of an individual follicle are not identical but heterogeneous. 4) Each follicular cell has a certain level of autonomy of growth and of function.
Similar articles
-
Transforming growth factor beta regulates thyroid growth. Role in the pathogenesis of nontoxic goiter.J Clin Invest. 1989 Mar;83(3):764-70. doi: 10.1172/JCI113955. J Clin Invest. 1989. PMID: 2921318 Free PMC article.
-
[Pathogenetic problems of goiter].Arkh Patol. 1981;43(4):88-93. Arkh Patol. 1981. PMID: 6112977 Review. Russian.
-
Pathogenesis of heterogeneity in human multinodular goiter. A study on growth and function of thyroid tissue transplanted onto nude mice.J Clin Invest. 1985 Nov;76(5):1992-2002. doi: 10.1172/JCI112199. J Clin Invest. 1985. PMID: 4056062 Free PMC article.
-
Histomorphological and immunohistochemical evidence that human nodular goiters grow by episodic replication of multiple clusters of thyroid follicular cells.J Clin Endocrinol Metab. 1992 Oct;75(4):1151-8. doi: 10.1210/jcem.75.4.1400886. J Clin Endocrinol Metab. 1992. PMID: 1400886
-
Immunoglobulins affecting thyroid growth: a continuing controversy.J Clin Endocrinol Metab. 1995 May;80(5):1506-8. doi: 10.1210/jcem.80.5.7744993. J Clin Endocrinol Metab. 1995. PMID: 7744993 Review. No abstract available.