Review
Interventions for the Treatment of Obstructive Sleep Apnea in Adults: A Health Technology Assessment [Internet]
Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2017 Mar.
- PMID: 30601604
- Bookshelf ID: NBK535532
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Review
Interventions for the Treatment of Obstructive Sleep Apnea in Adults: A Health Technology Assessment [Internet]
Excerpt
The aim of this health technology assessment (HTA) was to assess the clinical effectiveness, cost-effectiveness, patient perspectives and experiences, ethical issues, implementation issues, and environmental impacts of positive airway pressure (PAP) devices, expiratory positive airway pressure (EPAP) valves, oral appliances (OAs), surgery, and lifestyle modifications for the treatment of OSA in adults.
Copyright © 2017 Canadian Agency for Drugs and Technologies in Health.
Conflict of interest statement
Dr. Almeida received funding from Braebon, SomnoDent, Philips Respironics, and aveoTSD. She also participated in the 2015 510(k) process for the Braebon-DentiTrac compliance chip but received no remuneration. Dr. Kendzerska received funding from the ResMed Foundation Research Grant in 2011.
Sections
- External Reviewers
- Authorship
- Acknowledgements
- Conflicts of Interest
- Abbreviations
- Protocol Amendments
- Executive Summary
- Introduction
- Objectives
- Clinical Review
- Economic Evaluation
- Patient Perspectives and Experiences Review
- Ethics Analysis
- Implementation Issues
- Environmental Impact
- Discussion
- Conclusions
- References
- Appendix 1. Literature Search Strategy
- Appendix 2. Study Selection Flowchart (Research Question 1)
- Appendix 3. List of Included Studies (Research Question 1)
- Appendix 4. List of Excluded Studies (Research Question 1)
- Appendix 5. Quality Assessment Questions (Research Question 1)
- Appendix 6. Characteristics of Included Systematic Reviews (Research Question 1)
- Appendix 7. Characteristics of Included Systematic Reviews Arranged by Comparisons (Research Question 1)
- Appendix 8. Outcomes Reported by Included Systematic Reviews (Research Question 1)
- Appendix 9. Characteristics of Included Primary Studies (Research Question 1)
- Appendix 10. Summary of Quality or Risk of Bias Assessments Conducted by Included Systematic Reviews (Research Question 1)
- Appendix 11. Quality Assessment of Included Systematic Reviews (Research Question 1)
- Appendix 12. Quality Assessment of Included Network Meta-Analyses (Research Question 1)
- Appendix 13. Quality Assessment of Included Primary Studies With Cochrane Risk of Bias (Research Question 1)
- Appendix 14. Quality Assessment of Included Primary Studies With Robans (Research Question 1)
- Appendix 15. Validity of Outcomes Measures
- Appendix 16. Overlap of Primary Studies Across Included Systematic Reviews (Research Question 1)
- Appendix 17. Coverage in Canada (Research Question 2)
- Appendix 18. Characteristic of Existing Published Economic Evaluations on Treatments for Obstructive Sleep Apnea (Research Question 2)
- Appendix 19. Simplified Diagrammatic Representation of the Decision-Analytic Model (Research Question 2)
- Appendix 20. Description of Key Clinical Characteristics in Which Data Were Taken as Treatment Estimates for the Economic Model (Research Question 2)
- Appendix 21. Sensitivity Analysis Results Under a Lifetime Perspective (Research Question 2)
- Appendix 22. PRISMA Flow Diagram of Literature Search and Selection Process (Research Question 2)
- Appendix 23. Potentially Relevant Reports (Research Question 2)
- Appendix 24. Data Abstraction Form (Research Question 3)
- Appendix 25. Quality Assessment Instrument — Qualitative Studies (Research Question 3)
- Appendix 26. Quality Assessment Instrument — Survey Studies (Research Question 3)
- Appendix 27. Quality Assessment Instrument — Systematic Review (Research Question 3)
- Appendix 28. Selection of Included Studies (Research Question 3)
- Appendix 29. List of Included Studies (Research Question 3)
- Appendix 30. List of Remaining Eligible Studies (Research Question 3)
- Appendix 31. List of Excluded Studies, With Reasons (Research Question 3)
- Appendix 32. Characteristics of Included Studies (Research Question 3)
- Appendix 33. Characteristics of the Included Study Participants (Research Question 3)
- Appendix 34. Critical Appraisal of the Included Studies (Research Question 3)
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