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. 2019 Jan 3;380(1):97-98.
doi: 10.1056/NEJMc1811055.

Deaths in Colorado Attributed to Kratom

Affiliations

Deaths in Colorado Attributed to Kratom

Ken Gershman et al. N Engl J Med. .
No abstract available

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References

    1. Gottlieb S Statement from FDA Commissioner Scott Gottlieb, M.D., on the agency’s scientific evidence on the presence of opioid compounds in kratom, underscoring its potential for abuse: additional adverse events associated with kratom use identified. Silver Spring, MD: Food and Drug Administration, 2018.
    1. Kruegel AC, Grundmann O. The medicinal chemistry and neuropharmacology of kratom: a preliminary discussion of a promising medicinal plant and analysis of its potential for abuse. Neuropharmacology 2018;134(Pt A):108–20. - PubMed
    1. Warner ML, Kaufman NC, Grundmann O. The pharmacology and toxicology of kratom: from traditional herb to drug of abuse. Int J Legal Med 2016;130:127–38. - PubMed
    1. Varadi A, Marrone GF, Palmer TC, et al. Mitragynine/co- rynantheidine pseudoindoxyls as opioid analgesics with mu ag- onism and delta antagonism, which do not recruit β-arrestin-2. J Med Chem 2016;59:8381–97. - PMC - PubMed
    1. FDA warns companies selling illegal, unapproved kratom products marketed for opioid cessation, pain treatment, and other medical uses. Press release of the Food and Drug Administration, May 22, 2018. (https://www.fda.gov/newsevents/news-room/pressannouncements/ucm608447.htm).