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Review
. 2019 Jan;21(1):2-8.
doi: 10.1038/s41556-018-0227-8. Epub 2019 Jan 2.

Haematopoiesis in the era of advanced single-cell technologies

Sten Eirik W Jacobsen  1   2   3   4   5 , Claus Nerlov  6
Affiliations
Review

Haematopoiesis in the era of advanced single-cell technologies

Sten Eirik W Jacobsen et al. Nat Cell Biol. 2019 Jan.

Abstract

The molecular and functional characterization of single cells at scale has emerged as a key driver to unravel tissue biology. Thus, it is important to understand the strengths and limitations of transcriptomic approaches, molecular barcoding and functional assays used to study cellular properties at the single-cell level. Here, we review recent relevant work from the haematopoietic system and discuss how to interpret and integrate data obtained with different technologies.

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