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Review
. 1988 Jul;14(7):3-7.

Fragile X syndrome: a major cause of X-linked mental retardation

M G Butler  1
Affiliations
Review

Fragile X syndrome: a major cause of X-linked mental retardation

M G Butler. Compr Ther. 1988 Jul.
No abstract available

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Figures

Figure 1
Figure 1
An example of a fragile X syndrome pedigree showing affected males (shaded), percentage fragile X chromosome expression, and carrier females (represented by a dot in the open circles).
Figure 2
Figure 2
Schematic drawing and photograph of a fragile X chromosome. The arrows indicate the location of the fragile site.
Figure 3
Figure 3
Frontal and profile views of a 28-year-old male with the fragile X syndrome, showing large prominent ears, prominent forehead and supraorbital ridges, and long, narrow face.
See this image and copyright information in PMC

References

    1. Martin JP, Bell J. A pedigree of mental defect showing sex linkage. J Neurol Psychiatry. 1943;6:154–157. - PMC - PubMed
    1. Opitz JM. On the gates of hell and a most unusual gene. Am J Med Genet. 1986;23:1–10. - PubMed
    1. Turner G, Brookwell R, Daniel A, et al. Heterozygous expression of X-linked mental retardation and the X chromosome marker (fraX) (q27) N Engl J Med. 1980;303:662–664. - PubMed
    1. Herbst D, Miller J. Non specific X-linked mental retardation: II. The frequency in British Columbia. Am J Med Genet. 1980;7:461–469. - PubMed
    1. Lubs HA. A marker X chromosome. Am J Med Genet. 1969;21:231–244. - PMC - PubMed

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