Bilirubin as an important physiological modulator of oxidative stress and chronic inflammation in metabolic syndrome and diabetes: a new aspect on old molecule
- PMID: 30603284
- PMCID: PMC6224966
- DOI: 10.1007/s13340-016-0288-5
Bilirubin as an important physiological modulator of oxidative stress and chronic inflammation in metabolic syndrome and diabetes: a new aspect on old molecule
Conflict of interest statement
This article does not report any original studies with human or animal subjects that were performed by any of the authors.T. Inoguchi received speaker honoraria from Boehringer Ingelheim GmbH, Mitsubishi Tanabe Pharma Corporation, Novo Nordisk Pharma Ltd., Taisho Toyama Pharmaceutical Co. Ltd., Sanofi K.K., Astellas Pharma Inc., Kowa Pharmaceutical Co. Ltd., Novartis Pharma K.K., AstraZeneca K.K., Ono Pharmaceutical Co. Ltd., Takeda Pharmaceutical Co. Ltd., Eli Lilly Co. Ltd., Kissei Pharmaceutical Co. Ltd., Dainippon Pharmaceutical Co. Ltd. N. Sonoda received speaker honoraria from Takeda Pharmaceutical Co. Ltd., AstraZeneca K.K., Mitsubishi Tanabe Pharma Corporation. T. Inoguchi received scholarship grants from Dainippon Sumitomo Pharmaceutical Co. Ltd., Mitsubishi Tanabe Pharma Corporation, Astellas Pharma Inc., Ono Pharmaceutical Co. Ltd., Daiichi Sankyo Co. Ltd., Taisho Toyama Pharmaceutical Co. Ltd., Novo Nordisk Pharma Ltd., Eli Lilly Co. Ltd. Y. Maeda has no conflict of interest.
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References
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- Fukui M, Tanaka M, Shiraishi E, et al. Relationship between serum bilirubin and albuminuria in patients with type 2 diabetes. Kidney Int. 2008;74(1197–20):1. - PubMed
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- Yasuda M, Kiyohara Y, Wang JJ, et al. High serum bilirubin levels and diabetic retinopathy: the Hisayama Study. Opthalmology. 2011;118:1423–1428. - PubMed
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