Ion channels PIEZOs identified as the long-sought baroreceptor mechanosensors for blood pressure control, and other updates on autonomic research
- PMID: 30604163
- DOI: 10.1007/s10286-018-00588-3
Ion channels PIEZOs identified as the long-sought baroreceptor mechanosensors for blood pressure control, and other updates on autonomic research
Keywords: Atomoxetine; Autonomic failure; Baroreflex; Orthostatic hypotension; Pyridostigmine.
Comment on
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PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex.Science. 2018 Oct 26;362(6413):464-467. doi: 10.1126/science.aau6324. Science. 2018. PMID: 30361375 Free PMC article.
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Synergistic Pressor Effect of Atomoxetine and Pyridostigmine in Patients With Neurogenic Orthostatic Hypotension.Hypertension. 2019 Jan;73(1):235-241. doi: 10.1161/HYPERTENSIONAHA.118.11790. Hypertension. 2019. PMID: 30571543 Free PMC article. Clinical Trial.
References
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- Shibao C, Martinez J, Palma JA, Kaufmann H, Biaggioni I (2017) Norepinephrine levels predicts the improvement in orthostatic symptoms after atomoxetine in patients with neurogenic orthostatic hypotension. Neurology 88:P5.320
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