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Comment
. 2019 Feb;29(2):93-94.
doi: 10.1038/s41422-018-0126-3.

Probiotic fengycins dis(Agr)ee with Staphylococcus aureus colonization

Lawton K Chung  1 , Manuela Raffatellu  2   3   4
Affiliations
Comment

Probiotic fengycins dis(Agr)ee with Staphylococcus aureus colonization

Lawton K Chung et al. Cell Res. 2019 Feb.
No abstract available

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Figures

Fig. 1
Fig. 1
Bacillus eliminates intestinal Staphylococcus aureus colonization. a Fengycins produced by wild-type B. subtilis compete with Agr autoinducing peptides (AIPs) and block AgrC-dependent quorum sensing in S. aureus, thus reducing the expression of virulence factors and eliminating intestinal colonization by the pathogen. b A B. subtilis mutant defective in fengycin synthesis (ΔfenA) fails to inhibit S. aureus quorum sensing, virulence factor expression, and colonization
See this image and copyright information in PMC

Comment on

  • Pathogen elimination by probiotic Bacillus via signalling interference.
    Piewngam P, Zheng Y, Nguyen TH, Dickey SW, Joo HS, Villaruz AE, Glose KA, Fisher EL, Hunt RL, Li B, Chiou J, Pharkjaksu S, Khongthong S, Cheung GYC, Kiratisin P, Otto M. Piewngam P, et al. Nature. 2018 Oct;562(7728):532-537. doi: 10.1038/s41586-018-0616-y. Epub 2018 Oct 10. Nature. 2018. PMID: 30305736 Free PMC article.

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