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Review
. 2018 Dec;21(4):343-353.
doi: 10.4048/jbc.2018.21.e47. Epub 2018 Oct 29.

Current Approaches in Development of Immunotherapeutic Vaccines for Breast Cancer

Adil Allahverdiyev  1 , Gamze Tari  1 , Melahat Bagirova  1 , Emrah Sefik Abamor  1
Affiliations
Review

Current Approaches in Development of Immunotherapeutic Vaccines for Breast Cancer

Adil Allahverdiyev et al. J Breast Cancer. 2018 Dec.

Abstract

Cancer is the leading cause of death worldwide. In developed as well as developing countries, breast cancer is the most common cancer found among women. Currently, treatment of breast cancer consists mainly of surgery, chemotherapy, hormone therapy, and radiotherapy. In recent years, because of increased understanding of the therapeutic potential of immunotherapy in cancer prevention, cancer vaccines have gained importance. Here, we review various immunotherapeutic breast cancer vaccines including peptide-based vaccines, whole tumor cell vaccines, gene-based vaccines, and dendritic cell vaccines. We also discuss novel nanotechnology-based approaches to improving breast cancer vaccine efficiency.

Keywords: Breast neoplasms; Immunology; Immunotherapy; Vaccines.

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Conflict of interest statement

CONFLICT OF INTEREST: The authors declare that they have no competing interests.

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