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. 2019 Jan;98(1):e13953.
doi: 10.1097/MD.0000000000013953.

Differences in treatment outcomes between ultrasound-guided percutaneous microwave ablation and endoscopic thyroidectomy for patients with papillary thyroid microcarcinoma: Protocol for a systematic review and meta-analysis

Yan Shen  1 , Miao Liu  1 , Jie He  1 , Shu Wu  1 , Yong-Lin Wan  1 , Jun Ding  2 , Xiao-Yan Cai  3 , Xiao-Hong Fu  1
Affiliations

Differences in treatment outcomes between ultrasound-guided percutaneous microwave ablation and endoscopic thyroidectomy for patients with papillary thyroid microcarcinoma: Protocol for a systematic review and meta-analysis

Yan Shen et al. Medicine (Baltimore). 2019 Jan.

Abstract

Background: The differences in treatment outcomes between ultrasound (US)-guided percutaneous microwave ablation (PMWA) and endoscopic thyroidectomy for patients with papillary thyroid microcarcinoma (PTMC) remains unknown.

Methods: An electronic search will be performed for randomized controlled trials or observational studies that reported recurrence and mortality rates in PTMC patients with US-guided PMWA or endoscopic thyroidectomy. Hazard ratios with their 95% confidence intervals will be calculated using fixed- or random-effects models according to heterogeneity.

Results: This study will present the differences in treatment outcomes between US-guided PMWA and endoscopic thyroidectomy for patients with PTMC by pooling the results of individual studies.

Conclusion: The results of this study would provide vigorous evidence in this issue and offer the guidance to both clinical decision-making and future research.

Ethics and dissemination: Ethical approval is not applicable for this study.

Prospero registration number: CRD42018112320.

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Conflict of interest statement

The authors report no conflicts of interest.

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