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Editorial
. 2018 Nov;6(Suppl 1):S75.
doi: 10.21037/atm.2018.10.49.

A pathogenic hierarchy for synovial fibroblasts in rheumatoid arthritis

Mohammed H Abuwarwar  1 , Konstantin Knoblich  1 , Anne L Fletcher  1
Affiliations
Editorial

A pathogenic hierarchy for synovial fibroblasts in rheumatoid arthritis

Mohammed H Abuwarwar et al. Ann Transl Med. 2018 Nov.
No abstract available

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Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Comment on

  • Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis.
    Mizoguchi F, Slowikowski K, Wei K, Marshall JL, Rao DA, Chang SK, Nguyen HN, Noss EH, Turner JD, Earp BE, Blazar PE, Wright J, Simmons BP, Donlin LT, Kalliolias GD, Goodman SM, Bykerk VP, Ivashkiv LB, Lederer JA, Hacohen N, Nigrovic PA, Filer A, Buckley CD, Raychaudhuri S, Brenner MB. Mizoguchi F, et al. Nat Commun. 2018 Feb 23;9(1):789. doi: 10.1038/s41467-018-02892-y. Nat Commun. 2018. PMID: 29476097 Free PMC article.

References

    1. Gibofsky A. Overview of epidemiology, pathophysiology, and diagnosis of rheumatoid arthritis. Am J Manag Care 2012;18:S295-302. - PubMed
    1. Turner JD, Filer A. The role of the synovial fibroblast in rheumatoid arthritis pathogenesis. Curr Opin Rheumatol 2015;27:175-82. 10.1097/BOR.0000000000000148 - DOI - PubMed
    1. Lefevre S, Meier FMP, Neumann E, Muller-Ladner U. Role of synovial fibroblasts in rheumatoid arthritis. Curr Pharm Des;21:130-41. 10.2174/1381612820666140825122036 - DOI - PubMed
    1. Filer A, Ward LSC, Kemble S, et al. Identification of a transitional fibroblast function in very early rheumatoid arthritis. Ann Rheum Dis 2017;76:2105-12. 10.1136/annrheumdis-2017-211286 - DOI - PMC - PubMed
    1. Karouzakis E, Raza K, Kolling C, et al. Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis. Sci Rep 2018;8:7370. 10.1038/s41598-018-24240-2 - DOI - PMC - PubMed