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Case Reports
. 2018 Dec 26;6(16):1210-1216.
doi: 10.12998/wjcc.v6.i16.1210.

Chondromyxoid fibroma of the temporal bone: A case report and review of the literature

Ying-Mei Zheng  1 , He-Xiang Wang  2 , Cheng Dong  3
Affiliations
Case Reports

Chondromyxoid fibroma of the temporal bone: A case report and review of the literature

Ying-Mei Zheng et al. World J Clin Cases. .

Abstract

Background: Chondromyxoid fibroma (CMF) is a rare benign bone tumour of cartilaginous origin, which usually affects the metaphysis of the long bone. Involvement of the temporal bone is extremely rare. Patients with CMF in the temporal bone can present some neurological deficits due to involvement of surrounding neural structures.

Case summary: We present the first case of histopathologically proven CMF originating in the temporal bone and involving the hypoglossal canal in a 40-year-old woman. Hypoglossal nerve paralysis was identified on the cranial nerve examination. The patient underwent surgical excision and was neurologically normal except for mild left facial palsy on 5-mo follow-up examination after surgery. In the current report, the major characteristics and computed tomography/magnetic resonance imaging features of the lesion are discussed. Furthermore, previous literature regarding this pathology is reviewed.

Conclusion: The current study presents the first case of temporal bone CMF involving the hypoglossal canal.

Keywords: Case report; Chondromyxoid fibroma; Hypoglossal canal; Magnetic resonance imaging; Temporal bone.

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Conflict of interest statement

Conflict-of-interest statement: All the authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Axial computed tomography scan demonstrates a well-defined mass with a sclerotic rim and a scalloped margin originating from the mastoid portion of the temporal bone. A: The ipsilateral hypoglossal canal (arrow head) and the jugular foramen (arrow) were eroded by the mass. The contralateral hypoglossal canal (blank arrow head) and the jugular foramen (blank arrow) were normal; B: The left mastoid portion of the facial nerve canal was invaded by the tumour (blank arrow). Intratumoral calcification was noted in the tumour (arrow head).
Figure 2
Figure 2
Magnetic resonance imaging findings of the lesion. A-C: The lesion is hypointensity on axial T1-weighted image (A, arrow), heterogeneous hyperintensity on axial T2-weighted image (B, arrow), and enhances peripherally (C, arrow); D, E: The coronal contrast enhanced MR images show that the tumour invaded the left hypoglossal canal (D, arrow) and the left jugular foramen (E, arrow). The contralateral hypoglossal canal (D, blank arrow) and the jugular foramen (E, blank arrow) were normal.
Figure 3
Figure 3
High-power view of resected specimen showing a myxoid lesion consisting of cartilage material, admixed with spindle-shaped cells and bland stromal cells (H and E staining, ×200).
Figure 4
Figure 4
Postoperative magnetic resonance imaging scans. A, B: The axial T1-weighted image (A) and gadolinium-enhanced T1-weighted image (B) show that the mass originated from the mastoid portion of the temporal bone and displayed contrast enhancement before it was excised (arrow).
See this image and copyright information in PMC

References

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