An exercise-induced messenger boosts memory in Alzheimer's disease

Xu Chen¹, Li Gan^{2

3}

Affiliations

¹ Gladstone Institutes, Department of Neurology, University of California San Francisco, San Francisco CA, USA.
² Gladstone Institutes, Department of Neurology, University of California San Francisco, San Francisco CA, USA. lig2033@med.cornell.edu.
³ Helen and Robert Appel Alzheimer's Disease Research Institute, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA. lig2033@med.cornell.edu.

Comment

Xu Chen et al. Nat Med. 2019 Jan.

. 2019 Jan;25(1):20-21.

doi: 10.1038/s41591-018-0311-4.

Xu Chen¹, Li Gan^{2

3}

¹ Gladstone Institutes, Department of Neurology, University of California San Francisco, San Francisco CA, USA.
² Gladstone Institutes, Department of Neurology, University of California San Francisco, San Francisco CA, USA. lig2033@med.cornell.edu.
³ Helen and Robert Appel Alzheimer's Disease Research Institute, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA. lig2033@med.cornell.edu.

No abstract available

Comment on

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models.
Lourenco MV, Frozza RL, de Freitas GB, Zhang H, Kincheski GC, Ribeiro FC, Gonçalves RA, Clarke JR, Beckman D, Staniszewski A, Berman H, Guerra LA, Forny-Germano L, Meier S, Wilcock DM, de Souza JM, Alves-Leon S, Prado VF, Prado MAM, Abisambra JF, Tovar-Moll F, Mattos P, Arancio O, Ferreira ST, De Felice FG. Lourenco MV, et al. Nat Med. 2019 Jan;25(1):165-175. doi: 10.1038/s41591-018-0275-4. Epub 2019 Jan 7. Nat Med. 2019. PMID: 30617325 Free PMC article.

1. Alzheimer’s Association. Alzheimer’s & Dementia 14, 367–429 (2018).
1. Arnold, S. E. et al. Nat. Rev. Neurol. 14, 168–181 (2018). - DOI
1. Maliszewska-Cyna, E., Lynch, M., Oore, J. J., Nagy, P. M. & Aubert, I. Curr. Alzheimer Res. 14, 47–60 (2017). - DOI
1. Lourenco, M. V. et al. Nat. Med. http://doi.org/10.1038/s41591-018-0275-4 (2018).
1. Walsh, D. M. et al. Nature 416, 535–539 (2002). - DOI