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. 2019 Jan;21(1):31-45.
doi: 10.1007/s12094-018-02010-w. Epub 2019 Jan 8.

SEOM clinical guidelines in advanced and recurrent breast cancer (2018)

J I Chacón López-Muñiz  1   2 , L de la Cruz Merino  3 , J Gavilá Gregori  4 , E Martínez Dueñas  5 , M Oliveira  6 , M A Seguí Palmer  7 , I Álvarez López  8 , S Antolin Novoa  9 , M Bellet Ezquerra  10 , S López-Tarruella Cobo  11
Affiliations

SEOM clinical guidelines in advanced and recurrent breast cancer (2018)

J I Chacón López-Muñiz et al. Clin Transl Oncol. 2019 Jan.

Abstract

Although the metastasic breast cancer is still an incurable disease, recent advances have increased significantly the time to progression and the overall survival. However, too much information has been produced in the last 2 years, so a well-based guideline is a valuable document in treatment decision making. The SEOM guidelines are intended to make evidence-based recommendations on how to manage patients with advanced and recurrent breast cancer to achieve the best patient outcomes based on a rational use of the currently available therapies. To assign a level of certainty and a grade of recommendation the United States Preventive Services Task Force guidelines methodology was selected as reference.

Keywords: Advanced; Breast cancer; Guidelines; Loco-regional recurrence; SEOM.

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Conflict of interest statement

Conflict of interest

JICH reports advisory boards and travel grants from Bristol Myers Squibb, Roche, Novartis, Celgene, Pierre Fabre, Astrazeneca, Shire, MSD, Merck and Pfizer, outside the submitted work. LCM reports advisory boards and speaking from Bristol Myers Squibb, MSD, Merck, Novartis and Roche, and Research Grants from MSD, Merck, Celgene and Roche. JG reports personal fees from Roche and Novartis during the conduct of the study. EMD reports speaker fees and advisory boards from Pfizer, Novartis, AstraZeneca, Eisai, Pierre-Fabre and Roche, personal fees from Roche, and Coordinator of electronic book of breast cancer sponsored by Novartis. MO reports personal fees from Roche/Genentech, outside the submitted work. MAS reports personal fees and non-financial support from Roche, Pfizer and Novartis, and personal fees from EISAI, outside the submitted work. IA reports personal fees from Pfizer, Novartis, Roche, Astrazeneca y Palex, non financial-support from Pfizer and Roche, and grants from Pfizer, Novartis, Roche and Astrazeneca during the conduct of the study. SA has nothing to disclose. MB reports advisory boards from Pfizer, Novartis and Lilly, honoraria from Novrtis and Pfizer and travel grants from Pfizer and Roche, outside the submitted work, SLT reports personal fees from Astra Zeneca, Novartis, Roche, Pfizer, Celgene, Pierre Fabre, Eisai; non-financial support from Novartis, Celgene, Pfizer and Pierre Fabre during the conduct of the study.

Ethical approval

The current study has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

Informed consent

For this type of study formal consent is not required.

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