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Review
. 2018 Dec 11:6:619.
doi: 10.3389/fchem.2018.00619. eCollection 2018.

Magnetic Drug Delivery: Where the Field Is Going

Paige M Price  1 , Waleed E Mahmoud  2 , Ahmed A Al-Ghamdi  2 , Lyudmila M Bronstein  1   2   3
Affiliations
Review

Magnetic Drug Delivery: Where the Field Is Going

Paige M Price et al. Front Chem. .

Abstract

Targeted delivery of anticancer drugs is considered to be one of the pillars of cancer treatment as it could allow for a better treatment efficiency and less adverse effects. A promising drug delivery approach is magnetic drug targeting which can be realized if a drug delivery vehicle possesses a strong magnetic moment. Here, we discuss different types of magnetic nanomaterials which can be used as magnetic drug delivery vehicles, approaches to magnetic targeted delivery as well as promising strategies for the enhancement of the imaging-guided delivery and the therapeutic action.

Keywords: iron oxide; magnetic drug delivery; magnetic implant; magnetic targeting; theranostics.

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Figures

Figure 1
Figure 1
(A) SEM images of an array of printed tetrapod microstructures. (B) Schematic illustrating the mechanical release mechanism. (C) Track (red line) of a sperm-hybrid motor under magnetic guidance in the horizontal and vertical planes. (D) Image sequence of a sperm release process when the arms hit the corner of a polydimethylsiloxane wall. Blue arrows point at the sperm head. Time lapse in min:s (Xu et al., 2018). Reproduced with the permission of the copyright holder [American Chemical Society].
Figure 2
Figure 2
Schematic representation of the iMushbot action (Bhuyan et al., 2017). It is being reproduced with the permission of the copyright holder [American Chemical Society].
See this image and copyright information in PMC

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