Chromosomes: Keeping Centromeric Chromatin Tidy through S Phase
- PMID: 30620916
- DOI: 10.1016/j.cub.2018.11.044
Chromosomes: Keeping Centromeric Chromatin Tidy through S Phase
Abstract
The centromere, the chromosomal locus where the kinetochore is assembled in mitosis, is defined epigenetically, and its location must be remembered with each cell cycle. Recent studies elucidate how centromere identity is faithfully maintained despite challenges imposed by DNA replication.
Copyright © 2018 Elsevier Ltd. All rights reserved.
Comment on
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Inheritance of CENP-A Nucleosomes during DNA Replication Requires HJURP.Dev Cell. 2018 Nov 5;47(3):348-362.e7. doi: 10.1016/j.devcel.2018.09.003. Epub 2018 Oct 4. Dev Cell. 2018. PMID: 30293838 Free PMC article.
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Centromere DNA Destabilizes H3 Nucleosomes to Promote CENP-A Deposition during the Cell Cycle.Curr Biol. 2018 Dec 17;28(24):3924-3936.e4. doi: 10.1016/j.cub.2018.10.049. Epub 2018 Nov 29. Curr Biol. 2018. PMID: 30503616 Free PMC article.
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