A breakthrough in readthrough? Could geneticin lead the way to effective treatment for cystinosis nonsense mutations?
- PMID: 30623245
- DOI: 10.1007/s00467-018-4173-2
A breakthrough in readthrough? Could geneticin lead the way to effective treatment for cystinosis nonsense mutations?
Keywords: CTNS mutation; Children; Cystinosis; Geneticin; Genetics; Readthrough.
Comment on
-
The aminoglycoside geneticin permits translational readthrough of the CTNS W138X nonsense mutation in fibroblasts from patients with nephropathic cystinosis.Pediatr Nephrol. 2019 May;34(5):873-881. doi: 10.1007/s00467-018-4094-0. Epub 2018 Nov 9. Pediatr Nephrol. 2019. PMID: 30413946
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources